polyploidy
- Guideline or reference source
- ICHS2 Guidance on genotoxicity testing and data interpretation for pharmaceuticals intended for human use
- Definition
- Numerical deviation of the modal number of chromosomes in a cell, with approximately whole multiples of the haploid number. Endoreduplication is a morphological form of polyploidy in which chromosome pairs are associated at metaphase as “diplochromosomes”.
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