structure-activity relationships
- Guideline or reference source
- ICHM7 Assessment and control of dna reactive (mutagenic) impurities in pharmaceuticals to limit potential carcinogenic risk
- Definition
- In the context of this guideline, refers to the relationship between the molecular (sub) structure of a compound and its mutagenic activity using Structure-Activity Relationships derived from experimental data.
- Abbreviation for
- SAR
- Narrower Term
- quantitative structure-activity relationships
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