antimicrobial resistance
- Guideline or reference source
- WHO Glossary
- Definition
- Antimicrobial resistance corresponds to the emergence and spread of microbes that are resistant to cheap and effective first-choice, or "first-line" antimicrobial drugs. The bacterial infections which contribute most to human disease are also those in which emerging and microbial resistance is most evident: diarrheal diseases, respiratory tract infections, meningitis, sexually transmitted infections, and hospital-acquired infections. Some important examples include penicillin-resistant Streptococcus pneumonia, vancomycin-resistant enterococci, methicillin-resistant Staphylococcus aureus, multi-resistant salmonellae, and multi-resistant Mycobacterium tuberculosis. The development of resistance to drugs commonly used to treat malaria is of particular concern, as is the emerging resistance to anti-HIV drugs.
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