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quantitation limit
Guideline or reference source
ICHQ2 Validation of analytical procedures
Definition
The quantitation limit of an individual analytical procedure is the lowest amount of analyte in a sample which can be quantitatively determined with suitable precision and accuracy. The quantitation limit is a parameter of quantitative assays for low levels of compounds in sample matrices, and is used particularly for the determination of impurities and/or degradation products.
Broader Term
validation parameters
Related Term
accuracy
analytical procedure
detection limit
linearity
precision
range
robustness
specificity
 

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