microheterogeneity
- Guideline or reference source
- ISO11238 IDMP Data elements and structures for the unique identification and exchange of regulated information on substances
- Definition
- substances isolated together that contain minor differences in glycosylation, or post-translational modification such as glycosylation or sequence heterogeneity NOTE 1 Microheterogeneity is not a defining characteristic of either substances or specified substances. NOTE 2 Microheterogeneity consists of variability in the type of glycosylation (biantennary, triantennary), extent of glycosylation at a given site (site occupancy), sequence heterogeneity due to polymorphism in source material, translation errors, variable proteolytic processing or other.
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