co-chromatography
- Guideline or reference source
- UNODC Glossary of terms for quality assurance and good laboratory practice
- Definition
- Procedure for the identification of an unknown substance by chromatographic comparison with a known substance in which, prior to the chromatographic step(s), the purified test solution is divided into two parts and: • One part is chromatographed as such; • The other part has the standard analyte that is to be identified added to it and the resulting solution is then chromatographed. The amount of standard analyte has to be similar to the estimated amount of the analyte in the test solution. If the unknown substance is the same as the added standard analyte, the chromatographic peaks from the two samples will have the same retention time and shape.
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