baseline imbalance
- Guideline or reference source
- CDISC Glossary of terms
- ICHE9 Statistical principles for clinical trials
- Definition
- A systematic error in creating intervention groups, such that they differ with respect to prognosis. That is, the groups differ in measured or unmeasured baseline characteristics because of the way participants were selected or assigned. NOTE: also used to mean that the participants are not representative of the population of all possible participants
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